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Pentafluorobenzoic acid : ウィキペディア英語版 | Pentafluorobenzoic acid
Pentafluorobenzoic acid (PFBA) is an organofluorine compound with the formula C7F5CO2H. It is a white crystalline powder that has a high solubility in water. Its pKa of 1.48 indicates that it is a strong acid.〔Prakash, G. K. S.; Hu, J. "Pentafluorobenzoic Acid" e-EROS Encyclopedia of Reagents for Organic Synthesis, 2005. 〕 == Preparation== Pentafluorobenzoic acid is prepared by treating pentafluorophenyllithium (or pentafluorophenyl Grignard reagent) with carbon dioxide. These reagents are usually prepared in situ from pentafluorobenzene and bromopentafluorobenzene.〔 It arises via the reaction of perfluorotoluene with trifluoroacetic acid and antimony pentafluoride.〔Yaroslav V. Zonov, Victor M. Karpov, Vyacheslav E. Platonov "Transformation of perfluorinated benzocycloalkenes and alkylbenzenes to their carbonyl derivatives under the action of CF3COOH/SbF5" Journal of Fluorine Chemistry, 2007, vol. 128, pp. 1058-1064. 〕
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